Systems and methods are described for detecting and initiating a response to an environmental anomaly in a shipping container. Generally, a system includes two sets of ID nodes within and outside the container and a command node mounted to the container. The command node is specially adapted to monitor the different sets of ID nodes for unanticipated non-broadcasting according to communication profiles for respective ID nodes in each set and detect an unresponsive group of ID nodes and what set of ID nodes the unresponsive ones are in. The command node identifies the anomaly when the number of unresponsive ID nodes exceeds a threshold setting, automatically generates an alert notification on the anomaly with an alert level setting based upon whether the unresponsive ID nodes are in the first and/or second set of ID nodes, and initiates a mediation response by transmitting the notification to the transit vehicle transceiver.