Invention Grant
- Patent Title: Medicinal agent-containing molecular assembly which uses amphiphilic block polymer
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Application No.: US16334175Application Date: 2016-09-20
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Publication No.: US11224578B2Publication Date: 2022-01-18
- Inventor: Isao Hara , Eiichi Ozeki , Shunsaku Kimura , Takayuki Sato
- Applicant: SHIMADZU CORPORATION , KYOTO UNIVERSITY
- Applicant Address: JP Kyoto; JP Kyoto
- Assignee: SHIMADZU CORPORATION,KYOTO UNIVERSITY
- Current Assignee: SHIMADZU CORPORATION,KYOTO UNIVERSITY
- Current Assignee Address: JP Kyoto; JP Kyoto
- Agency: Sughrue Mion, PLLC
- International Application: PCT/JP2016/077744 WO 20160920
- International Announcement: WO2018/055681 WO 20180329
- Main IPC: A61K9/51
- IPC: A61K9/51 ; A61K47/14 ; A61K47/34 ; A61K9/107 ; A61K33/243 ; B82Y5/00 ; C08L77/00
Abstract:
Provided is a molecular assembly (for example, a polymeric micelle nanoparticle) which is capable of efficiently encapsulating a fat-soluble drug. A molecular assembly comprising: an amphiphilic block polymer A1 comprising a hydrophilic block having a sarcosine unit and a hydrophobic block having a lactic acid unit; a hydrophobic polymer A2 having a lactic acid unit; a fatty acid triglyceride; and a fat-soluble drug. Examples of the fat-soluble drug include miriplatin.
Public/Granted literature
- US20190269624A1 MEDICINAL AGENT-CONTAINING MOLECULAR ASSEMBLY WHICH USES AMPHIPHILIC BLOCK POLYMER Public/Granted day:2019-09-05
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