A multi-degree-of-freedom (Multi-DOF) 3D printing device includes a printer mechanism, a rotatable platform, a visual inspection system, and a control system. The printing mechanism includes a print head. The printing mechanism and the rotatable platform are combined to have three degrees of freedom of translation, and the rotatable platform has two degrees of freedom of rotation. The visual inspection system includes a camera mounted to nearby the print head and the relative position of camera and print head remains constant. The control system is configured to implement the printing process. The model is decomposed into several components, each of which could be printed in a single direction. After one component is printed out, the platform is then rotated so that the cutting plane for the component will be printed is horizontal.