A zipper manifold for use in wellbore operations includes a trunk line having a first longitudinal axis, an inlet on a first axial end, an outlet on a second axial end, and a first gate valve positioned between the inlet and the outlet, a block tee fluidly connecting the trunk line to a secondary line, the secondary line having a second longitudinal axis parallel to the first longitudinal axis, a second gate valve positioned along the secondary line, and an outlet head at an end of the secondary line.