The present invention provides an organic light emitting diode (OLED) display panel and a manufacturing method of the OLED display panel. The present invention improves a light transmittance of an entire array layer by reducing the number of thin film transistors in an array layer under a camera-under-panel (CUP) region, and at the same time, patterning a cathode layer corresponding to a position of the CUP region to improve a light transmittance of the cathode layer, so that the CUP region can provide clear imaging, and the CUP region can also display images normally.