Invention Grant
- Patent Title: Low-dose doxepin for treatment of sleep disorders in elderly patients
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Application No.: US14789911Application Date: 2015-07-01
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Publication No.: US11234954B2Publication Date: 2022-02-01
- Inventor: Roberta L. Rogowski , Susan Ellen Dube , Philip Jochelson , Neil Barton Kavey
- Applicant: Pernix Sleep, Inc. , ProCom One, Inc.
- Applicant Address: US NJ Morristown; US TX San Marcos
- Assignee: Pernix Sleep, Inc.,ProCom One, Inc.
- Current Assignee: Pernix Sleep, Inc.,ProCom One, Inc.
- Current Assignee Address: US NJ Morristown; US TX San Marcos
- Agency: Servilla Whitney LLC
- Main IPC: A61K31/355
- IPC: A61K31/355 ; A61K31/335

Abstract:
Methods of treating sleep disorders, particularly certain aspects of insomnia, in elderly patients (65 years and older) by administering initial daily dosages of doxepin of 1-3 mg. These ultra-low initial dosages are more effective in elderly versus non-elderly patients in decreasing wake time during sleep, latency to persistent sleep and wake time after sleep, and are particularly efficacious in treating those conditions in the last hour of an 8-hour sleep cycle. Also, the dosages described herein are safe for elderly individuals.
Public/Granted literature
- US20160030383A1 LOW-DOSE DOXEPIN FOR TREATMENT OF SLEEP DISORDERS IN ELDERLY PATIENTS Public/Granted day:2016-02-04
Information query
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