Invention Grant
- Patent Title: Solid dispersion
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Application No.: US16765575Application Date: 2018-11-28
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Publication No.: US11234984B2Publication Date: 2022-02-01
- Inventor: Shigeru Itai , Shuji Noguchi , Yasunori Iwao , Masuharu Hirano , Takashi Ohta , Tomio Yamakawa
- Applicant: Shizuoka Prefectural University Corporation , Nippon Chemiphar Co., Ltd.
- Applicant Address: JP Shizuoka; JP Tokyo
- Assignee: Shizuoka Prefectural University Corporation,Nippon Chemiphar Co., Ltd.
- Current Assignee: Shizuoka Prefectural University Corporation,Nippon Chemiphar Co., Ltd.
- Current Assignee Address: JP Shizuoka; JP Tokyo
- Agency: Wood Herron & Evans LLP
- Priority: JPJP2017-227807 20171128
- International Application: PCT/JP2018/043788 WO 20181128
- International Announcement: WO2019/107412 WO 20190606
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K9/19 ; A61K47/38

Abstract:
The present invention relates to a solid dispersion containing a compound represented by General Formula (I): wherein R1 is an unsubstituted phenyl group or a phenyl group substituted with a substituent; the substituent is an alkyl group having 1 to 8 carbon atoms, an alkyl group having 1 to 8 carbon atoms substituted with a halogen atom, an alkoxy group having 1 to 8 carbon atoms, an alkoxycarbonyl group having 2 to 8 carbon atoms, a formyl group, a carboxyl group, a halogen atom, a phenyl group or a phenoxy group; R2 is a cyano group or a nitro group; R3 is a hydroxyl group; X is an oxygen atom or —S(O)n—; n is an integer of 0 to 2; Y is an oxygen atom or a sulfur atom, or a pharmaceutically acceptable salt thereof and a hypromellose derivative.
Public/Granted literature
- US20200306251A1 SOLID DISPERSION Public/Granted day:2020-10-01
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