Invention Grant
- Patent Title: Methods and compositions related to glucocorticoid receptor antagonists and breast cancer
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Application No.: US16596342Application Date: 2019-10-08
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Publication No.: US11234990B2Publication Date: 2022-02-01
- Inventor: Deng Pan , Masha Kocherginsky , Suzanne D. Conzen
- Applicant: The University of Chicago
- Applicant Address: US IL Chicago
- Assignee: The University of Chicago
- Current Assignee: The University of Chicago
- Current Assignee Address: US IL Chicago
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K31/575
- IPC: A61K31/575 ; A61K45/06 ; A61K33/243 ; A61K31/282 ; A61K31/337 ; A61K31/357 ; A61K31/4745 ; A61K31/7068 ; A61K39/395 ; A61N5/00 ; A61J1/00 ; A61K31/567 ; A61K31/58
Abstract:
Embodiments of the invention are directed to methods of determining the prognosis of a breast cancer patient by evaluating the activity of the glucocorticoid receptor in tumor cells. Other embodiment include methods of treating breast cancer cells, particularly, chemo-resistant cells, with a glucocorticoid receptor antagonist and an anticancer agent or compound.
Public/Granted literature
- US20200030344A1 METHODS AND COMPOSITIONS RELATED TO GLUCOCORTICOID RECEPTOR ANTAGONISTS AND BREAST CANCER Public/Granted day:2020-01-30
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