Invention Grant
- Patent Title: Hybrid hepadnavirus cores carrying multiple malaria parasite epitopes
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Application No.: US16175681Application Date: 2018-10-30
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Publication No.: US11235045B2Publication Date: 2022-02-01
- Inventor: David R. Milich , David C. Whitacre
- Applicant: VLP Biotech, Inc.
- Applicant Address: US CA San Diego
- Assignee: VLP Biotech, Inc.
- Current Assignee: VLP Biotech, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Morrison & Foerster LLP
- Main IPC: A61K39/015
- IPC: A61K39/015 ; A61P33/06 ; C12Q1/70 ; A61K39/29 ; A61K39/295

Abstract:
The present disclosure relates to rodent hepadnavirus core antigens including one or more B cell and T cell epitopes of a malaria parasite antigen. More specifically, the present disclosure relates to hybrid woodchuck hepadnavirus core antigens that have been modified to diminish the antibody response to the core antigen so as to enhance the antibody response to fragments of malaria antigen(s) included therein.
Public/Granted literature
- US20190209672A1 HYBRID HEPADNAVIRUS CORES CARRYING MULTIPLE MALARIA PARASITE EPITOPES Public/Granted day:2019-07-11
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