Invention Grant
- Patent Title: Reaction medium containing water-surfactant mixture
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Application No.: US16088374Application Date: 2017-03-27
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Publication No.: US11236076B2Publication Date: 2022-02-01
- Inventor: Fabrice Gallou , Michael Parmentier , Jianguang Zhou , Pengfei Guo
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Francine F. Li
- Priority: WOPCT/CN2016/077703 20160329
- International Application: PCT/IB2017/051732 WO 20170327
- International Announcement: WO2017/168303 WO 20171005
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07C211/52 ; C07C269/06 ; C07D241/20 ; C07D333/64 ; C07D401/04 ; C07D403/14 ; C07D487/04

Abstract:
The present invention is directed to reaction mixtures comprising a water-surfactant mixture and a co-solvent. This technology reduced the amount of organic solvents needed for performing chemical reactions. Furthermore, compared to reaction mixtures lacking the co-solvent, solvation of the reactants and products of the chemical reaction is greatly enhanced, leading to a significantly improved yield, purity, reproducibility and robustness.
Public/Granted literature
- US20200299281A1 REACTION MEDIUM CONTAINING WATER-SURFACTANT MIXTURE Public/Granted day:2020-09-24
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