Invention Grant
- Patent Title: Highly active pyrazolo-piperidine substituted indole-2-carboxamides active against the hepatitis B virus (HBV)
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Application No.: US16760929Application Date: 2018-11-02
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Publication No.: US11236087B2Publication Date: 2022-02-01
- Inventor: Alastair Donald , Andreas Urban , Susanne Bonsmann , Anita Wegert , Jasper Springer
- Applicant: AiCuris GmbH & Co. KG
- Applicant Address: DE Wuppertal
- Assignee: AiCuris GmbH & Co. KG
- Current Assignee: AiCuris GmbH & Co. KG
- Current Assignee Address: DE Wuppertal
- Agency: Millen White Zelano and Branigan, PC
- Agent Richard Traverso
- Priority: EP17199676.2 20171102
- International Application: PCT/EP2018/000503 WO 20181102
- International Announcement: WO2019/086142 WO 20190509
- Main IPC: C07D471/04
- IPC: C07D471/04
Abstract:
The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
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