Invention Grant
- Patent Title: Antibodies and methods for the diagnosis and treatment of Epstein Barr virus infection
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Application No.: US16608386Application Date: 2018-04-25
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Publication No.: US11236151B2Publication Date: 2022-02-01
- Inventor: Wei Bu , Masaru Kanekiyo , Michael Gordon Joyce , Jeffrey I. Cohen
- Applicant: THE USA, as represented by the Secretary, Department of Health and Human Services , THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
- Applicant Address: US MD Bethesda; US MD Bethesda
- Assignee: THE USA, as represented by the Secretary, Department of Health and Human Services,THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
- Current Assignee: THE USA, as represented by the Secretary, Department of Health and Human Services,THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
- Current Assignee Address: US MD Bethesda; US MD Bethesda
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2018/029463 WO 20180425
- International Announcement: WO2018/200742 WO 20181101
- Main IPC: C07K16/08
- IPC: C07K16/08 ; C07K14/05 ; A61K38/00
Abstract:
Antibodies and compositions of matter useful for the detection, diagnosis and treatment of Epstein Barr Virus infection in mammals, and to methods of using those compositions of matter for the same. Also disclosed are proteins, referred to as anti-gp350 antibody probes, and anti-gp350 B-cell probes, that maintain the epitope structure of the CR2-binding region of gp350, but do not bind CR2.
Information query
