Invention Grant
- Patent Title: Antibodies to pyroglutamate amyloid-β and uses thereof
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Application No.: US16829029Application Date: 2020-03-25
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Publication No.: US11236155B2Publication Date: 2022-02-01
- Inventor: Bianca Van Broeck , Marc Mercken , Wilson Edwards , Sanjaya Singh , Jinquan Luo , Sherry La Porte , Rajkumar Ganesan , Chichi Huang
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agency: Grimes & Yvon LLP
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61K39/00 ; A61P25/28 ; A61K39/395
Abstract:
The invention provides antibodies or antigen binding fragments thereof that bind to 3pE Aβ and methods of making and using the antibodies or antigen binding fragments thereof, including use for formulations, administration and kits. The antibody and antigen binding fragments thereof and methods disclosed are useful for diagnosis, prognosis and treatment of Alzheimer's disease or other β-amyloid-related diseases.
Public/Granted literature
- US20200308261A1 Antibodies to Pyroglutamate Amyloid-B and Uses Thereof Public/Granted day:2020-10-01
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