Invention Grant
- Patent Title: Chimeric antigen receptors targeting CD-19
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Application No.: US16360281Application Date: 2019-03-21
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Publication No.: US11236161B2Publication Date: 2022-02-01
- Inventor: James N. Kochenderfer
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Bethesda
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Bethesda
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: A61K35/17
- IPC: A61K35/17 ; C07K14/705 ; C07K16/28 ; C07K14/725 ; C07K14/735 ; C07K16/30 ; C12N5/0783
Abstract:
The invention is directed to a chimeric antigen receptor (CAR) directed against CD19, which comprises an amino acid sequence of any one of SEQ ID NO: 1-SEQ ID NO: 13. The invention also provides T-cells expressing the CAR and methods for destroying malignant B-cells.
Public/Granted literature
- US20190202913A1 CHIMERIC ANTIGEN RECEPTORS TARGETING CD-19 Public/Granted day:2019-07-04
Information query
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