Invention Grant
- Patent Title: Mouse FcγammaRII-specific Fc antibody
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Application No.: US14422207Application Date: 2013-08-23
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Publication No.: US11236168B2Publication Date: 2022-02-01
- Inventor: Tomoyuki Igawa , Eriko Murata , Futa Mimoto
- Applicant: Chugai Seiyaku Kabushiki Kaisha
- Applicant Address: JP Tokyo
- Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Priority: JPJP2012-185865 20120824
- International Application: PCT/JP2013/072598 WO 20130823
- International Announcement: WO2014/030750 WO 20140227
- Main IPC: C07K16/28
- IPC: C07K16/28 ; G01N33/564 ; A61K39/395 ; G01N33/68 ; A61K49/00
Abstract:
The present inventors have successfully found a large number of Fc variants with remarkably increased binding activity against and/or binding selectivity for mouse FcγRII by introducing amino acid alteration(s) to the Fc region.
Public/Granted literature
- US20150203577A1 MOUSE FcgammaRII-SPECIFIC Fc ANTIBODY Public/Granted day:2015-07-23
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