- Patent Title: Proximity-based sortase-mediated protein purification and ligation
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Application No.: US16333196Application Date: 2017-09-14
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Publication No.: US11236177B2Publication Date: 2022-02-01
- Inventor: Andrew Tsourkas , Burcin Altun , Hejia Henry Wang , Feifan Yu
- Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Applicant Address: US PA Philadelphia
- Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee Address: US PA Philadelphia
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- International Application: PCT/US2017/051636 WO 20170914
- International Announcement: WO2018/053180 WO 20180322
- Main IPC: C07K16/40
- IPC: C07K16/40 ; C07K1/14 ; C07K7/06 ; C12N9/52 ; C07K19/00 ; C07K1/22
Abstract:
The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
Public/Granted literature
- US20200277403A1 PROXIMITY-BASED SORTASE-MEDIATED PROTEIN PURIFICATION AND LIGATION Public/Granted day:2020-09-03
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