A fluid injection process includes removing a core sample from a low permeability reservoir. The process also includes performing an imbibition test on a plurality of stage one surfactants, each stage one surfactant mixed with a first treatment fluid and using a portion of the core sample to obtain a wettability index or measurement of capillary pressure. The process includes selecting a stage one surfactant and performing an oil recovery test on a plurality of stage two surfactants, each stage two surfactant mixed with a second treatment fluid. The process includes selecting a stage two surfactant and injecting the selected stage one surfactant into a matrix of the low permeability reservoir. In addition, the method includes injecting the selected stage two surfactant into a fracture network of the low permeability reservoir.