Invention Grant
- Patent Title: Thermophile peptidoglycan hydrolase fusion proteins and uses thereof
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Application No.: US16375287Application Date: 2019-04-04
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Publication No.: US11236315B2Publication Date: 2022-02-01
- Inventor: David M. Donovan , Steven M. Swift
- Applicant: The United States of America, as Represented by the Secretary of Agriculture , University of Maryland
- Applicant Address: US DC Washington; US MD College Park
- Assignee: The United States of America, as Represented by the Secretary of Agriculture,University of Maryland
- Current Assignee: The United States of America, as Represented by the Secretary of Agriculture,University of Maryland
- Current Assignee Address: US DC Washington; US MD College Park
- Agent John D. Fado; Maria Restrepo-Hartwig
- Main IPC: C12N9/36
- IPC: C12N9/36 ; A23K20/147 ; A61P31/04 ; A61K38/00 ; A23K50/75 ; C12N15/62
Abstract:
The disclosure relates to chimeric recombinant lysins comprising at least one thermophile endolysin catalytic domain and at least one cell wall binding domain. Also disclosed are polynucleotides encoding the chimeric recombinant lysins, host cells expressing the chimeric recombinant lysins, and use of such chimeric recombinant lysins.
Public/Granted literature
- US20200318090A1 Thermophile Peptidoglycan Hydrolase Fusion Proteins and Uses Thereof Public/Granted day:2020-10-08
Information query
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