Invention Grant
- Patent Title: Modified polynucleotide
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Application No.: US16640213Application Date: 2018-08-17
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Publication No.: US11236334B2Publication Date: 2022-02-01
- Inventor: Hiroshi Abe , Zhaoma Shu
- Applicant: National University Corporation Nagoya University
- Applicant Address: JP Nagoya
- Assignee: National University Corporation Nagoya University
- Current Assignee: National University Corporation Nagoya University
- Current Assignee Address: JP Nagoya
- Agency: MH2 Technology Law Group, LLP
- Priority: JPJP2017-159770 20170822
- International Application: PCT/JP2018/030549 WO 20180817
- International Announcement: WO2019/039403 WO 20190228
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7088
Abstract:
The present invention addresses the problem of providing a technique for more conveniently delivering a polynucleotide in a less cytotoxic form into a cell. This problem is solved by a polynucleotide modified by a molecule that contains a structure that contains a disulfide bond and/or a thiol group.
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