Invention Grant
- Patent Title: RNA aptamers against transferrin receptor (TFR)
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Application No.: US15519074Application Date: 2015-10-15
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Publication No.: US11236341B2Publication Date: 2022-02-01
- Inventor: John J. Rossi , Sorah Yoon , Nagy Habib
- Applicant: City of Hope , Apterna Ltd
- Applicant Address: US CA Duarte; GB London
- Assignee: City of Hope,Apterna Ltd
- Current Assignee: City of Hope,Apterna Ltd
- Current Assignee Address: US CA Duarte; GB London
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- International Application: PCT/US2015/055792 WO 20151015
- International Announcement: WO2016/061386 WO 20160421
- Main IPC: C12N15/115
- IPC: C12N15/115 ; A61K31/7105 ; A61K51/00 ; A61P35/00 ; G01N33/574 ; C07K14/705 ; A61K47/54 ; A61K31/713 ; A61K45/06 ; G01N33/53
Abstract:
Provided herein, inter alia, are nucleic acid compounds capable of binding transferrin receptor on a cell and internalizing into said cell. The compositions provided herein may be useful for delivering therapeutic and diagnostic agents to a cell. Further provided are pharmaceutical compositions and methods of treatment using nucleic acid compounds provided herein.
Public/Granted literature
- US20170226515A1 RNA APTAMERS AGAINST TRANSFERRIN RECEPTOR (TFR) Public/Granted day:2017-08-10
Information query
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