Invention Grant
- Patent Title: Antibody producing non-human animals
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Application No.: US15652827Application Date: 2017-07-18
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Publication No.: US11237165B2Publication Date: 2022-02-01
- Inventor: Ton Logtenberg , Mark Throsby , Robert A. Kramer , Rui Daniel Pinto , Cornelis A. de Kruif , Erwin Houtzager
- Applicant: Merus N.V.
- Applicant Address: NL Utrecht
- Assignee: Merus N.V.
- Current Assignee: Merus N.V.
- Current Assignee Address: NL Utrecht
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: G01N33/569
- IPC: G01N33/569 ; C07K16/00 ; C07K16/22 ; C07K16/10 ; C07K16/24 ; C07K16/28 ; C07K16/32
Abstract:
Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is a common human, human-like, or humanized light chain. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal.
Public/Granted literature
- US20180031555A1 METHOD FOR SELECTING A SINGLE CELL EXPRESSING A HETEROGENEOUS COMBINATION OF ANTIBODIES Public/Granted day:2018-02-01
Information query
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