A multistage Doherty power amplifier and a transmitter are provided, and the multistage Doherty power amplifier includes: a generalized carrier amplifier, which is a nested 2-way inverted Doherty sub amplifier, and a generalized peaking amplifier, connected to the generalized carrier amplifier, which is a nested single ended sub amplifier or a nested 2-way normal Doherty sub amplifier, the generalized carrier amplifier and the generalized peaking amplifier are arranged in a generalized 2-way inverted Doherty power amplifier form. With the multistage Doherty power amplifier, signal power probability distribution function (PDF) oriented for a cost-effective multi stage Doherty PA design is applied, and 2-way normal and inverted Doherty PA cells are used as basic units to construct multistage Doherty PA with gain extension effect.