- Patent Title: Genetically modified non-human animal with human or chimeric TIM-3
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Application No.: US16409656Application Date: 2019-05-10
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Publication No.: US11240995B2Publication Date: 2022-02-08
- Inventor: Yuelei Shen , Jian Ni , Yanan Guo , Rui Huang , Meiling Zhang , Lei Zhao , Yang Bai
- Applicant: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Applicant Address: CN Beijing
- Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Current Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Current Assignee Address: CN Beijing
- Agency: Fish & Richardson P.C.
- Priority: CN201610994218.2 20161111,CN201711103773.2 20171110
- Main IPC: A01K67/027
- IPC: A01K67/027

Abstract:
The present disclosure relates to the genetically modified non-human animals that express a human or chimeric (e.g., humanized) T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), and methods of use thereof.
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