Invention Grant
- Patent Title: Benzonatate modified release solid tablets and capsules
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Application No.: US16668479Application Date: 2019-10-30
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Publication No.: US11241411B2Publication Date: 2022-02-08
- Inventor: Andrea Nelson , Quin-Zene Chen , Harsh Mehta , Yu-Hsing Tu
- Applicant: Tris Pharma Inc.
- Applicant Address: US NJ Monmouth Junction
- Assignee: Tris Pharma Inc.
- Current Assignee: Tris Pharma Inc.
- Current Assignee Address: US NJ Monmouth Junction
- Agency: Howson & Howson LLP
- Agent Cathy A. Kodroff
- Main IPC: A61K9/28
- IPC: A61K9/28 ; A61K31/245 ; A61K31/09 ; A61K31/25 ; A61K45/06 ; A61K9/20 ; A61K9/24 ; A61K9/00 ; A61K9/50

Abstract:
A modified release benzonatate solid tablet or capsule is described which comprises a benzonatate adsorbate in a matrix with a sufficient amount of one or more pharmaceutically acceptable modified release pH-independent, substances to provide a modified release profile to the benzonatate, wherein there is substantially no benzonatate release from the tablet or capsule in the buccal cavity and no more than about 25% release of the benzonatate within 1 hour as determined in an in vitro dissolution assay.
Public/Granted literature
- US20200163926A1 BENZONATATE MODIFIED RELEASE SOLID TABLETS AND CAPSULES Public/Granted day:2020-05-28
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