Invention Grant
- Patent Title: Autophagy inducers for treatment of CNS conditions
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Application No.: US16480885Application Date: 2018-01-25
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Publication No.: US11241436B2Publication Date: 2022-02-08
- Inventor: Congcong He , Sui Huang , Chen Wang , Altea Rocchi , Juan Jose Marugan , Marc Ferrer , Samarjit Patnaik , Yuchi Chen , Kevin Frankowski , Frank J. Schoenen
- Applicant: Northwestern University , The United States of America,as represented by the Secretary,Department of Health and Human Services , University of Kansas
- Applicant Address: US IL Evanston; US MD Bethesda; US KS Lawrence
- Assignee: Northwestern University,The United States of America,as represented by the Secretary,Department of Health and Human Services,University of Kansas
- Current Assignee: Northwestern University,The United States of America,as represented by the Secretary,Department of Health and Human Services,University of Kansas
- Current Assignee Address: US IL Evanston; US MD Bethesda; US KS Lawrence
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2018/015293 WO 20180125
- International Announcement: WO2018/140630 WO 20180802
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61P25/30 ; A61K31/704
Abstract:
The invention provides a compound of formula (I): wherein R1, R2, R3, and R4 are as defined herein, ginsenoside Rg2 of structure (II): or a combination thereof, for use in treating or preventing a condition responsive to the induction of autophagy in a brain of a mammal in need thereof.
Public/Granted literature
- US20200009146A1 AUTOPHAGY INDUCERS FOR TREATMENT OF CNS CONDITIONS Public/Granted day:2020-01-09
Information query
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