Invention Grant
- Patent Title: Dipeptidyl ketoamide meta-methoxyphenyl derivatives and uses thereof
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Application No.: US17051896Application Date: 2019-05-03
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Publication No.: US11242312B2Publication Date: 2022-02-08
- Inventor: Jesús Llenas Calvo , Miriam Royo Expósito , Unai Elezcano Donaire , Enrique Vázquez Tatay , Marta Melgarejo Díaz , Marta Isabel Barranco Gallardo , Eva Ma Medina Fuentes
- Applicant: LANDSTEINER GENMED, S.L.
- Applicant Address: ES Seville
- Assignee: LANDSTEINER GENMED, S.L.
- Current Assignee: LANDSTEINER GENMED, S.L.
- Current Assignee Address: ES Seville
- Agency: Olive Law Group, PLLC
- Agent Tristan A. Fuierer
- Priority: EP18382306 20180503
- International Application: PCT/EP2019/061369 WO 20190503
- International Announcement: WO2019/211434 WO 20191107
- Main IPC: C07C235/84
- IPC: C07C235/84 ; C07K5/02 ; C07C237/22 ; C07C259/06

Abstract:
The present invention relates to dipeptidyl ketoamide m-methoxyphenyl derivatives and their use in the treatment of diseases and conditions associated with elevated calpain activity, such as heart injury caused by infarction, ischemia with or without reperfusion, neurodegenerative disorders, malaria, diabetic nephropathy, neurotoxicity induced by HIV virus, cancer, and fibrotic diseases.
Public/Granted literature
- US20210317075A1 DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF Public/Granted day:2021-10-14
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