Invention Grant
- Patent Title: Inhibition of OLIG2 activity
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Application No.: US16328551Application Date: 2017-08-25
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Publication No.: US11242323B2Publication Date: 2022-02-08
- Inventor: Graham Beaton , Stanton F. McHardy , Ambrosio Lopez, Jr. , Bismarck Campos , Hua-Yu Leo Wang
- Applicant: CURTANA PHARMACEUTICALS, INC.
- Applicant Address: US TX Austin
- Assignee: CURTANA PHARMACEUTICALS, INC.
- Current Assignee: CURTANA PHARMACEUTICALS, INC.
- Current Assignee Address: US TX Austin
- Agency: Wilson Sonsini Goodrich & Rosati
- International Application: PCT/US2017/048716 WO 20170825
- International Announcement: WO2018/039621 WO 20180301
- Main IPC: C07D239/48
- IPC: C07D239/48 ; A61P35/00 ; C07D401/12 ; C07D403/12 ; C07D405/12
Abstract:
Described herein are urea compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.
Public/Granted literature
- US20190389812A1 INHIBITION OF OLIG2 ACTIVITY Public/Granted day:2019-12-26
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