Invention Grant
- Patent Title: Mechanistic target of rapamycin signaling pathway inhibitors and therapeutic applications thereof
-
Application No.: US16313081Application Date: 2017-05-17
-
Publication No.: US11242346B2Publication Date: 2022-02-08
- Inventor: Chuangxing Guo , Youzhi Tong
- Applicant: SUZHOU KINTOR PHARMACEUTICALS, INC.
- Applicant Address: CN Jiangsu
- Assignee: SUZHOU KINTOR PHARMACEUTICALS, INC.
- Current Assignee: SUZHOU KINTOR PHARMACEUTICALS, INC.
- Current Assignee Address: CN Jiangsu
- Agency: Parker Highlander PLLC
- International Application: PCT/CN2017/084683 WO 20170517
- International Announcement: WO2017/219800 WO 20171228
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D519/00
Abstract:
Selective mTOR inhibitors of formulas (I)-(III), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from abnormal cell growth, functions, or behaviors mediated by an mTOR kinase and/or one or more PI3K enzyme, are provided. Such diseases and disorder include cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
Public/Granted literature
- US20200181147A1 MECHANISTIC TARGET OF RAPAMYCIN SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF Public/Granted day:2020-06-11
Information query
