Invention Grant
- Patent Title: Biocompatible modular tetrazine platform
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Application No.: US16496387Application Date: 2018-03-23
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Publication No.: US11242359B2Publication Date: 2022-02-08
- Inventor: Victor Goncalves , Franck Denat , Claire Bernhard , Coline Canovas
- Applicant: Centre national de la recherche scientifique , Université de Bourgogne
- Applicant Address: FR Paris; FR Dijon
- Assignee: Centre national de la recherche scientifique,Université de Bourgogne
- Current Assignee: Centre national de la recherche scientifique,Université de Bourgogne
- Current Assignee Address: FR Paris; FR Dijon
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: FR1752451 20170324,FR1759851 20171019
- International Application: PCT/EP2018/057520 WO 20180323
- International Announcement: WO2018/172543 WO 20180927
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D403/14 ; C07D405/14 ; A61K39/00 ; C07F5/02 ; C07D405/12
Abstract:
A modular tetrazine platform, can be used as diagnostic, theragnostic agent and/or medicinal product. An inverse electron demand Diels-Alder reaction can be used for synthesizing bifunctionalized tetrazines, which can be obtained from monofunctionalised tetrazines.
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