Invention Grant
- Patent Title: FOXM1-derived peptide, and vaccine including same
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Application No.: US15762436Application Date: 2016-10-06
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Publication No.: US11242365B2Publication Date: 2022-02-08
- Inventor: Sachiko Yamashita , Tetsuro Hikichi
- Applicant: OncoTherapy Science, Inc.
- Applicant Address: JP Kawasaki
- Assignee: OncoTherapy Science, Inc.
- Current Assignee: OncoTherapy Science, Inc.
- Current Assignee Address: JP Kawasaki
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: JPJP2015-200221 20151008
- International Application: PCT/JP2016/079717 WO 20161006
- International Announcement: WO2017/061523 WO 20170413
- Main IPC: C07K7/06
- IPC: C07K7/06 ; A61K35/17 ; A61K38/00 ; A61K35/12 ; C12N5/10 ; C07K14/47 ; C07K16/32 ; A61K35/15 ; C07K16/30 ; A61K39/00 ; G01N33/50

Abstract:
The present invention provides FOXM1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
Public/Granted literature
- US20180346512A1 FOXM1-DERIVED PEPTIDE, AND VACCINE INCLUDING SAME Public/Granted day:2018-12-06
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