Invention Grant
- Patent Title: Chimeric receptor with ligand binding exodomain and cytokine and T cell signalling endodomains
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Application No.: US15770110Application Date: 2016-10-21
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Publication No.: US11242377B2Publication Date: 2022-02-08
- Inventor: Martin Pulé , Shaun Cordoba , Matteo Righi
- Applicant: AUTOLUS LIMITED
- Applicant Address: GB London
- Assignee: AUTOLUS LIMITED
- Current Assignee: AUTOLUS LIMITED
- Current Assignee Address: GB London
- Agency: Marshall, Gerstein & Borun LLP
- Priority: GB1518816 20151023
- International Application: PCT/GB2016/053290 WO 20161021
- International Announcement: WO2017/068360 WO 20170427
- Main IPC: C07K14/715
- IPC: C07K14/715 ; C07K14/705 ; C07K19/00 ; C07K16/30 ; C12N5/0783 ; C07K16/28 ; C07K14/725 ; A61K39/00 ; A61K35/17
Abstract:
The present invention provides a chimeric receptor which comprises: a ligand-binding exodomain; and an endodomain which comprises: (i) a cytokine receptor endodomain; and (ii) an intracellular T cell signalling domain.
Public/Granted literature
- US20180312570A1 Receptor Public/Granted day:2018-11-01
Information query
