Invention Grant
- Patent Title: ROR1 antibody compositions and related methods
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Application No.: US16805102Application Date: 2020-02-28
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Publication No.: US11242388B2Publication Date: 2022-02-08
- Inventor: Christoph Rader , Haiyong Peng , Roger Beerli , Lorenz Waldmeier , Ulf Grawunder
- Applicant: NBE-Therapeutics AG , The Scripps Research Institute
- Applicant Address: CH Basel; US CA La Jolla
- Assignee: NBE-Therapeutics AG,The Scripps Research Institute
- Current Assignee: NBE-Therapeutics AG,The Scripps Research Institute
- Current Assignee Address: CH Basel; US CA La Jolla
- Agency: Morgan, Lewis & Bockius LLP
- Agent Christopher J. Betti; Alia M. Orbin
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61K47/68 ; C07K14/725 ; A61K47/69 ; C07K14/705 ; C12N9/12 ; A61P35/02 ; A61P35/00 ; A61K39/00
Abstract:
The invention provides antibodies, antibody drug conjugates, antibody-based fragments or antibody fragments (antigen-binding fragments), as well as antibody drug conjugates (ADCs) and chimeric antigen receptors (CARs), that specifically recognize human ROR1 and related compositions. Also provided in the invention are methods of using such antibodies in various diagnostic and therapeutic applications.
Public/Granted literature
- US20200299381A1 ROR1 Antibody Compositions and Related Methods Public/Granted day:2020-09-24
Information query
