Invention Grant
- Patent Title: Anti-CD137 molecules and use thereof
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Application No.: US16108018Application Date: 2018-08-21
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Publication No.: US11242395B2Publication Date: 2022-02-08
- Inventor: Peter Peizhi Luo , Fangyong Du , Yan Li , Guizhong Liu , Jun Chen , Xiaohong She , Peter Cheung
- Applicant: Adagene Inc.
- Applicant Address: KY Grand Cayman
- Assignee: Adagene Inc.
- Current Assignee: Adagene Inc.
- Current Assignee Address: KY Grand Cayman
- Agency: Morrison Foerster LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61K39/00 ; A61P35/00 ; A61K45/06

Abstract:
The present disclosure provides antibodies that bind to human CD137 or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, and for the treatment of cancer.
Public/Granted literature
- US20190055314A1 ANTI-CD137 MOLECULES AND USE THEREOF Public/Granted day:2019-02-21
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