Invention Grant
- Patent Title: Sialyltransferase ST3GAL6 as a marker for multiple myeloma
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Application No.: US15597961Application Date: 2017-05-17
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Publication No.: US11242566B2Publication Date: 2022-02-08
- Inventor: Siobhan Glavey , Lokesh Joshi , Michael O'Dwyer
- Applicant: NATIONAL UNIVERSITY OF IRELAND, GALWAY
- Applicant Address: IE Galway
- Assignee: NATIONAL UNIVERSITY OF IRELAND, GALWAY
- Current Assignee: NATIONAL UNIVERSITY OF IRELAND, GALWAY
- Current Assignee Address: IE Galway
- Agency: Leason Ellis LLP
- Priority: EP12188596 20121015
- Main IPC: A61K31/7105
- IPC: A61K31/7105 ; C12Q1/6886 ; G01N33/574
Abstract:
The present invention relates to the sialyltransferase ST3GAL6 for use as a biomarker for multiple myeloma, and especially as a marker for myelomas with inferior survival rates. The inventors have shown that glycosylation gene expression is dysregulated in Multiple Myeloma and that overexpression of the sialyltransferase ST3GAL6 is associated with inferior survival rates in patients.
Public/Granted literature
- US20170327899A1 SIALYLTRANSFERASE ST3GAL6 AS A MARKER FOR MULTIPLE MYELOMA Public/Granted day:2017-11-16
Information query
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