Systems, apparatus and methods for operating an environmental control system that delivers dehumidified outdoor air into a conditioned space through an air valve. The method includes establishing CO2 setpoints corresponding to a ventilation outdoor air flow rate and a dehumidification outdoor air flow rate, determining a humidity metric of the conditioned space, and delivering outside air to the conditioned space at the ventilation outdoor air flow rate or dehumidification outdoor air flow rate based upon the humidity metric. The outside air may be tempered with return air from the conditioned space. The dehumidification CO2 set point is determined by predicting the dehumidification CO2 set point based on the airflow quantity per occupant and the relationship of the occupant predicted water vapor emission rate and CO2 emission rate.