This invention is to collectively manage the timing to replace the multiple gas cylinders, and is a cylinder management system that manages multiple gas cylinders that supply a utility gas of a calibration gas to multiple gas analysis device and that comprises multiple pressure sensors that that detect a pressure of each of the multiple gas cylinders, and a management device that calculates a cylinder gas residual quantity in each gas cylinder based on the pressure detected by each pressure sensor and manages the timing to replace each gas cylinder.