A hose to be evaluated is installed on a fixing frame in a preset shape, and a strain gauge and markers are attached to a surface of the hose. During a course of application of predetermined internal pressure to the hose, strain data is acquired using the strain gauge and an image of an external shape of the hose is captured using a camera device to acquire image data. Based on the strain data and the image data acquired, a change in the shape of the hose between a plurality of time points at identical internal pressure is determined. Such hose fatigue resistance evaluation system can determine changes in the degree of deformation of a hose over time due to repeated application of internal pressure.