Invention Grant
- Patent Title: Kits and methods for prediction and treatment of preeclampsia
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Application No.: US15773978Application Date: 2016-11-07
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Publication No.: US11243213B2Publication Date: 2022-02-08
- Inventor: Adi L. Tarca , Piya Chaemsaithong , Tinnakorn Chaiworapongsa , Sonia S. Hassan , Roberto Romero
- Applicant: WAYNE STATE UNIVERSITY , THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE
- Applicant Address: US MI Detroit; US MD Bethesda
- Assignee: WAYNE STATE UNIVERSITY,THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE
- Current Assignee: WAYNE STATE UNIVERSITY,THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE
- Current Assignee Address: US MI Detroit; US MD Bethesda
- Agency: Lee & Hayes, P.C.
- Agent Tanya M. Harding
- International Application: PCT/US2016/060825 WO 20161107
- International Announcement: WO2017/079741 WO 20170511
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/68 ; C12Q1/6883 ; A61K35/16
Abstract:
Biomarkers tests which can be used to predict a positive or negative risk of preeclampsia are described. More specifically, a panel of biomarkers including MMP-7 and gpIIbIIIa, described. The test is useful to predict preeclampsia when a biological sample is obtained between the 16th and 22nd week of pregnancy. Prediction later in pregnancy can be achieved by a combination of Siglec-6, Activin A, ALCAM, and/or FCN2.
Public/Granted literature
- US20180328937A1 KITS AND METHODS FOR PREDICTION AND TREATMENT OF PREECLAMPSIA Public/Granted day:2018-11-15
Information query
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