A processor or system includes a processor core to execute a set of instructions to determine that a memory encryption mode is enabled. The memory encryption mode is to cause data stored to memory to be encrypted and data retrieved from the memory to be decrypted. The processor core is further to determine that a debug mode has been enabled and, responsive to a determination that the debug mode has been enabled, generate a second encryption key different than a first encryption key employed before reboot of a computing system. The processor core is further to transmit the second encryption key to a cryptographic engine for use in encryption and decryption of the data according to the memory encryption mode.