Modifying item packaging according to determined replenishment times. According to embodiments of the present disclosure, a method for modifying item packaging is described herein. An order is received from a user for an item. An exhaustion time for the item is calculated according to an inventory database for the user. An initial replenishment time for the item is calculated. A package quantity is calculated according to the exhaustion time, shipment time, initial replenishment time, and inventory database.