Clinical application of oxidative compositions, alone or in combination with polymer or salt stabilizers, for use in bone proliferation applications, such as spinal surgery, arthroplasty, or osteosarcoma. Additional applications include use in dental artificial tooth implants, orthopedic implantable prostheses for small and large bones, implantation into other surgical sites (e.g., dental implants, bone graft additive, face reconstruction, etc.) where bone growth is desired.