- Patent Title: Glycoconjugate vaccines comprising basic units of a molecular construct expressing built-in multiple epitopes for the formulation of a broad-spectrum vaccine against infections due to enteropathogenic bacteria
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Application No.: US16666367Application Date: 2019-10-28
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Publication No.: US11246919B2Publication Date: 2022-02-15
- Inventor: Massimo Porro
- Applicant: BIOSYNTH S.R.L.
- Applicant Address: IT Rapolano Terme
- Assignee: BIOSYNTH S.R.L.
- Current Assignee: BIOSYNTH S.R.L.
- Current Assignee Address: IT Rapolano Terme
- Agency: Hedman & Costigan, P.C.
- Agent James V. Costigan; Kathleen A. Costigan
- Priority: ITMI2014A001361 20140725
- Main IPC: A61K39/02
- IPC: A61K39/02 ; A61K39/108 ; A61K39/112 ; A61K39/00 ; A61K47/64

Abstract:
The present invention refers to new glycoconjugate antigens expressing built-in multiple epitopes and to polyvalent glycoconjugate vaccines intended for the protection of mammalians, and particularly for the protection of the human population from enteropathogenic bacteria, such as the Gram-positive anaerobic bacterium Clostridium difficile and the Gram-negative bacteria Salmonella typhi, Escherichia coli, Vibrio cholerae, Shigella flexneri, Salmonella typhimurium, Salmonella enteritidis, Salmonella paratyphi A, Shigella sonnei, Shigella dysenteriae, Salmonella cholerasuis, Klebsiella, Enterobacter, Pseudomonas aeruginosa and/or from viral gastrointestinal infections due to human noroviruses.
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