Invention Grant
- Patent Title: Pharmaceutical formulations of nitrite and uses thereof
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Application No.: US16307739Application Date: 2017-06-06
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Publication No.: US11247902B2Publication Date: 2022-02-15
- Inventor: Amol Soin , Christopher Kevil , Kyle Chan , Anthony Giordano
- Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
- Applicant Address: US LA Baton Rouge
- Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
- Current Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
- Current Assignee Address: US LA Baton Rouge
- Agency: Holoubek Patent Law, LLC
- Agent Charlotte Holoubek
- International Application: PCT/US2017/036166 WO 20170606
- International Announcement: WO2017/214157 WO 20171214
- Main IPC: A61P25/02
- IPC: A61P25/02 ; C01B21/50 ; A61K31/381 ; A61K31/095 ; A61K31/137 ; A61K31/445 ; A61K33/00
Abstract:
The present invention relates to pharmaceutical compositions of nitrites such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The pharmaceutical compositions, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO2−). The pharmaceutical compositions of the invention are useful, for example, for treating or reducing pain, improving symptoms of a microvascular disease, and improving nerve conduction velocity.
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