Invention Grant
- Patent Title: PCSK9 inhibitors and methods of use thereof
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Application No.: US16744929Application Date: 2020-01-16
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Publication No.: US11248001B2Publication Date: 2022-02-15
- Inventor: Michael H. Serrano-Wu , Mark Chambers , Erica Goldsmith , Jason Tierney , Karamjit Jandu , David Clark , Paul Hinchliffe
- Applicant: ASTRAZENECA AB
- Applicant Address: SE Sodertalje
- Assignee: ASTRAZENECA AB
- Current Assignee: ASTRAZENECA AB
- Current Assignee Address: SE Sodertalje
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D491/107 ; A61P9/00 ; A61P3/06 ; C07D403/14 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D471/10 ; C07D487/10 ; C07D495/04 ; C07D498/04 ; A61K45/06

Abstract:
The invention relates to novel heteroaryl compounds of Formula (I) and pharmaceutical preparations thereof. The invention further relates to methods of treating or preventing cardiovascular diseases, and methods treating sepsis or septic shock, using the novel heterocyclic compounds disclosed herein.
Public/Granted literature
- US20200291041A1 PCSK9 Inhibitors and Methods of Use Thereof Public/Granted day:2020-09-17
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