Invention Grant
- Patent Title: Binding moieties for biofilm remediation
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Application No.: US16746708Application Date: 2020-01-17
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Publication No.: US11248040B2Publication Date: 2022-02-15
- Inventor: Lawrence M. Kauvar , Stefan Ryser , Angeles Estelles , Reyna J. Simon , Lauren Opremcak Bakaletz , Steven David Goodman
- Applicant: TRELLIS BIOSCIENCE, LLC
- Applicant Address: US CA Redwood City
- Assignee: TRELLIS BIOSCIENCE, LLC
- Current Assignee: TRELLIS BIOSCIENCE, LLC
- Current Assignee Address: US CA Redwood City
- Agency: FisherBroyles, LLP
- Agent Victoria L. Boyd; Jason M. Pass
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/12 ; A61K39/40 ; A61K45/06 ; A61K49/00 ; C07K14/31 ; G01N33/569 ; C12Q1/18 ; G01N33/566 ; C12N15/86 ; A61K35/12

Abstract:
Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies secreted by human B lymphocytes. Methods to prevent formation of or to dissolve biofilms with these binding agents are also described. Immunogens for eliciting antibodies to disrupt biofilms are also described.
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