Invention Grant
- Patent Title: Multivalent CD20-binding molecule comprising Shiga toxin A subunit effector polypeptides and enriched compositions thereof
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Application No.: US15290266Application Date: 2016-10-11
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Publication No.: US11248061B2Publication Date: 2022-02-15
- Inventor: Eric Poma , Erin Willert , Jason Kim , Jack Higgins , Jensing Liu , Rodney Flores-Lefranc
- Applicant: Molecular Templates, Inc.
- Applicant Address: US TX Georgetown
- Assignee: Molecular Templates, Inc.
- Current Assignee: Molecular Templates, Inc.
- Current Assignee Address: US TX Georgetown
- Agency: Cooley LLP
- Main IPC: C07K19/00
- IPC: C07K19/00 ; C07K16/28 ; C07K14/25 ; A61K38/16 ; A61K38/17 ; A61K39/00 ; C07K16/18 ; A61P35/00

Abstract:
Provided herein are multivalent CD20-binding molecules, and compositions thereof, for use in selective killing of specific cell types and/or as therapeutics for the treatment of a variety of diseases, including cancer, tumors, and immune disorders. Certain multivalent CD20-binding molecules can be used to deliver agents into CD20-expressing cells, collecting diagnostic information, and/or monitoring the treatment of diseases, such as cancers, tumors, and immune disorders.
Public/Granted literature
Information query