Invention Grant
- Patent Title: Temperature-responsive gel having LCST with no volume phase transition, and production method therefor
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Application No.: US16471224Application Date: 2017-12-20
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Publication No.: US11248104B2Publication Date: 2022-02-15
- Inventor: Takayuki Nonoyama , Jian Ping Gong , Yong Woo Lee , Kumi Ota
- Applicant: National University Corporation Hokkaido University
- Applicant Address: JP Sapporo
- Assignee: National University Corporation Hokkaido University
- Current Assignee: National University Corporation Hokkaido University
- Current Assignee Address: JP Sapporo
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: JPJP2016-246385 20161220
- International Application: PCT/JP2017/045768 WO 20171220
- International Announcement: WO2018/117165 WO 20180628
- Main IPC: C08K5/098
- IPC: C08K5/098 ; C08J3/075

Abstract:
A temperature-responsive hydrogel which contains a carboxyl group-bearing polymer and a divalent-metal salt of an organic acid is provided. The carboxyl group-bearing polymer may be a homopolymer of a carboxyl group-bearing monomer or a copolymer of a plurality of monomers including the monomer. A method for producing the temperature-responsive hydrogel involves immersing a carboxyl group-bearing polymer in an aqueous solution of a divalent-metal salt of an organic acid. The concentration of the divalent-metal salt of an organic acid in the aqueous solution may be 50 mM to the saturation concentration. It is possible to provide a temperature-responsive gel having an LCST with no volume phase transition and a method for producing the temperature-responsive gel.
Public/Granted literature
- US20200087485A1 TEMPERATURE-RESPONSIVE GEL HAVING LCST WITH NO VOLUME PHASE TRANSITION, AND PRODUCTION METHOD THEREFOR Public/Granted day:2020-03-19
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