A liquid-cooling heat dissipation apparatus includes a water distribution box, a water collection box, a first radiating pipe, a second radiating pipe, a third radiating pipe, a fourth radiating pipe, and a pumping device. The channels in the liquid-cooling heat dissipation apparatus are connected in sequence to form a circuitous configuration. This allows the water to travel a longer distance in the liquid-cooling heat dissipation apparatus, so that the liquid-cooling heat dissipation apparatus can effectively cool the water and dissipate heat.