Invention Grant
- Patent Title: Immunological signatures and parameters predicting therapeutic responses to anti-TNF therapy
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Application No.: US15761238Application Date: 2016-09-27
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Publication No.: US11249090B2Publication Date: 2022-02-15
- Inventor: Lars Rogge , Silvia Menegatti , Maxime Dougados , Elisabetta Bianchi
- Applicant: INSTITUT PASTEUR , ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS , UNIVERSITE PARIS DESCARTES
- Applicant Address: FR Paris; FR Paris; FR Paris
- Assignee: INSTITUT PASTEUR,ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS,UNIVERSITE PARIS DESCARTES
- Current Assignee: INSTITUT PASTEUR,ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS,UNIVERSITE PARIS DESCARTES
- Current Assignee Address: FR Paris; FR Paris; FR Paris
- Agency: Arrigo, Lee, Guttman & Mouta-Bellum LLP
- Priority: EP15306536 20150929
- International Application: PCT/EP2016/072969 WO 20160927
- International Announcement: WO2017/055268 WO 20170406
- Main IPC: G01N33/68
- IPC: G01N33/68 ; C12Q1/6883 ; A61P19/02 ; A61K39/02 ; A61K39/145 ; A61K39/00
Abstract:
The invention relates to a method of predicting therapeutic responses to TNF blockers before anti-TNF therapy comprising analyzing immune parameters to selected stimuli in patients before therapy and its use for anti-TNF therapy. The invention relates also to a method of determining a predictive biomarker of response to anti-TNF therapy and to the use of the predictive biomarker obtained by the method.
Public/Granted literature
- US20180267058A1 IMMUNOLOGICAL SIGNATURES AND PARAMETERS PREDICTING THERAPEUTIC RESPONSES TO ANTI-TNF THERAPY Public/Granted day:2018-09-20
Information query
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