A computing environment can include a host system that maintains a guest system, and a hardware component configured to implement artificial intelligence (“AI”) methods of processing and analyzing date. The guest system can provide a virtual computing environment that receives a request to implement an AI application, and utilize a framework and a guest library to convert data from the AI application into an intermediate representation (“IR”). The host system can receive the IR with a virtual device (“VD”), and utilize an IR backend to translate the IR into hardware operations for the hardware component. Translated hardware operations can be provided to, and carried out by, the hardware component to provide an implementation of the AI application. Results of the hardware operations can be transmitted from the VD of the host system to a VD driver of the guest system, virtualizing the hardware component relative to the guest system.